Memory Changes Tied to Menopause

Posted by Brigham and Women's Hospital November 14, 2016

Many women experience changes in memory as they get older, and according to a study conducted by Brigham and Women’s Hospital (BWH) researchers, these changes are impacted by their menopausal status and not simply chronological age.

New research shows transition to menopause causes changes in memory circuitry.

New research shows transition to menopause causes changes in memory circuitry.

The study’s investigators found that women participating in the study who had lower levels of the sex hormone, estradiol – known to decline during the menopausal transition – performed more poorly on a verbal memory task than those who had higher levels regardless of age. Participants with lower estradiol levels also showed more changes in the brain circuitry that controls memory.

“Our findings underscore the incredible variability of the brain as we age and the critical importance and complexity of the impact of sex on aging, including the unique role of sex steroid hormones in memory function,” said senior author Jill Goldstein, PhD, director of Research at the Connors Center for Women’s Health and Gender Biology at BWH. “Maintaining intact memory function with age is one of the greatest public health challenges of our time, and applying a sex-dependent lens to the study of memory circuitry aging will help identify early antecedents of future memory decline and risk for Alzheimer’s disease.” Read More »

Ringing out 2012 – Most Popular HealthHub Posts

Posted by Brigham and Women's Hospital January 1, 2013

The blog team at Brigham and Women’s Hospital would like to close out 2012 with a selection of our most popular posts.  We’d also love to read about your favorites in our comments section.

We wish you a safe and happy New Year and look forward to sharing more health stories with you in 2013.

 

1.  What’s in a Face?

After suffering a disfiguring injury, Dallas Wiens receives the gift of a new face – the first full face transplant in the U.S. – at Brigham and Women’s Hospital.  The life-giving surgery, performed by a team of more than 30 physicians, nurses, anesthesiologists, and residents , provides Wiens with the typical facial features and function of any other man.

 

2.  Prostate Cancer Screening – Should I or Shouldn’t I?

Dr. Anthony D’Amico, Professor and Chief of Genitourinary Radiation Oncology at Brigham and Women’s Hospital and Chief of the Prostate Cancer Radiation Oncology Service at Dana-Farber/Brigham and Women’s Cancer Center, discusses the benefits of prostate cancer screening, particularly for younger men.

Read More »