Partners HealthCare Biobank – Advancing Personalized Medicine

Posted by Brigham and Women's Hospital November 19, 2015

20140404; Friday, April 4, 2014, Boston, MA, USA; Partners HealthCare Biobank leaders Susan A. Slaugenhaupt, MD, and Elizabeth Wood Karlson, MD, talk about the promise of the Biobank project in Dr. Slaugenhaupt's lab space inside the Massachusetts General Hospital Simches Research Building Friday morning April 4, 2014. background: "The Partners HealthCare Biobank is a large research program designed to help researchers understand how people’s health is affected by their genes, lifestyle, and environment. The Biobank collects and maintain samples and information from individuals who receive their care at Brigham and Women's Hospital, Spaulding Rehabilitation Hospital, and Massachusetts General Hospital. These materials will be used in research to better understand many different diseases." ~ adapted from Partners website Partners HealthCare annual report project with Hill Holliday ( 2014 © lightchaser photography )

Partners HealthCare Biobank leaders Dr. Elizabeth W. Karlson (left) and Dr. Susan A. Slaugenhaupt.

The Partners HealthCare Biobank is a program designed to help researchers at Brigham and Women’s Hospital, Massachusetts General Hospital, and other Partners HealthCare institutions understand how people’s health is affected by their genes, lifestyle, and environment.

By understanding a patient’s genetic makeup, physicians can screen more aggressively for diseases that their patients are predisposed to and develop plans to reduce the chances of developing specific diseases. Ultimately, the goal is to define and classify subgroups of patients based on how they respond to certain treatments, which will help physicians choose the best medications for individuals. This is known as personalized medicine.

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Crowdsourcing Medical Innovation

Posted by Brigham and Women's Hospital November 28, 2012

Dr. Robert Green, winner of the first BRIght Futures Prize.

On November 15, 2012, the Biomedical Research Institute (BRI) at Brigham and Women’s Hospital (BWH) held its first Research Day.  The day-long public celebration featured a discussion on the importance of medical research and included 150 poster presentations by leading BWH researchers on today’s hottest health topics, such as obesity, healthy aging, and personalized medicine.

But the highlight of BWH Research Day was the announcement of Dr. Robert Green as the winner of the $100,000 BRIght Futures Prize.  Just as exciting: the use of crowdsourcing, or relying on the collective wisdom of groups, to choose the winner.

Dr. Green was named the winner after nearly 6,500 people from around the world voted for the three finalists online.  Dr. Green and his research team are searching for effective and responsible ways to use DNA sequencing technology in newborns to help families understand a child’s genetic risk for developing diseases such as diabetes, heart disease, or cancer.

In addition to Dr. Green’s project, the other finalists included a project jointly led by Drs. Phil DeJager and Elizabeth Karlson, whose proposal focused on using genetics and electronic health records to treat multiple sclerosis and a project led by Dr. Robert Plenge, whose proposal focused on the use of technology to unravel the mysteries of the immune system. Read our recent blog post to learn and view more about all three projects.

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Looking for an Election with Three Great Candidates?

Posted by Brigham and Women's Hospital October 4, 2012

We have three great medical research ideas – but only one prize.

The Brigham and Women’s Hospital (BWH) Biomedical Research Institute (BRI) is going to award its first-ever $100,000 BRIght Futures Prize to one of three entrants next month, and they’re looking for your help.

Earlier this year, the BRI asked BWH staff to submit provocative medical questions that they would like to see answered by their research colleagues. From these responses, BRI leadership selected two themes and invited the BWH research community to design research projects to address these themes. These three projects were selected as finalists:


Exploring Genome Sequencing of Newborns – to determine responsible ways to use DNA sequencing to enhance patient care.

Robert C. Green, MD, MPH, BWH Division of Genetics, Department of Medicine

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