Posted by Brigham and Women's Hospital October 26, 2016
Dr. Christine Seidman, Director of the Cardiovascular Genetics Center at Brigham and Women’s Hospital, and her team have developed novel approaches to evaluate and care for patients with inherited heart disease and their families.
In some families, heart disease occurs more frequently than in the general public. Researchers at Brigham and Women’s Hospital have spent years studying heart disease in these families to pinpoint genetic changes that lead to the development of heart disease.
“Our team has pioneered diagnostic testing for patients at risk for genetic forms of heart disease,” said Dr. Christine Seidman, Director of the Cardiovascular Genetics Center at BWH. “We can now determine if an individual carries a dangerous genetic variant and intervene to treat or help prevent damage to the heart.”
Examples of inherited heart diseases include hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmias, Marfan syndrome, and inherited aortic aneurysms. Caring for someone with an inherited heart disease includes the patient’s family, particularly the patient’s siblings and children. Genetic testing can be performed to determine risk in these family members. Preventative measures or therapies Read More »
Posted by Brigham and Women's Hospital November 19, 2015
Partners HealthCare Biobank leaders Dr. Elizabeth W. Karlson (left) and Dr. Susan A. Slaugenhaupt.
The Partners HealthCare Biobank is a program designed to help researchers at Brigham and Women’s Hospital, Massachusetts General Hospital, and other Partners HealthCare institutions understand how people’s health is affected by their genes, lifestyle, and environment.
By understanding a patient’s genetic makeup, physicians can screen more aggressively for diseases that their patients are predisposed to and develop plans to reduce the chances of developing specific diseases. Ultimately, the goal is to define and classify subgroups of patients based on how they respond to certain treatments, which will help physicians choose the best medications for individuals. This is known as personalized medicine.
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