The COcoa Supplement and Multivitamin Outcomes Study (COSMOS) is the most extensive study to date testing the roles of cocoa extract and a multivitamin in improving health.

Contributor: Dr. JoAnn Manson is Chief of the Division of Preventive Medicine at Brigham and Women’s Hospital (BWH). She is leading the COSMOS trial with BWH Dr. Howard Sesso, an associate epidemiologist at BWH.

Researchers at Brigham and Women’s Hospital and the Fred Hutchinson Cancer Research Center are collaborating in a new research study, known as the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), for the most extensive study to date testing the roles of cocoa extract and a multivitamin in improving health, including preventing heart disease and cancer.

Previous studies of cocoa flavanols conducted by researchers at BWH and other institutions have found that cocoa may reduce the risk of heart disease (including a short-term decrease in blood pressure), as well as slow age-related cognitive decline. BWH researchers have also previously found that multivitamin use modestly reduced cancer risk in a trial of more than 14,000 male physicians.

“COSMOS will allow us to further explore these promising nutritional supplements in both men and women as part of a large-scale national clinical trial,” said Dr. JoAnn Manson, Chief of the Division of Preventive Medicine at BWH and Co-Director of COSMOS with BWH epidemiologist Dr. Howard Sesso.

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