Posted by Brigham and Women's Hospital December 11, 2013
AERD is a common respiratory condition in people with asthma who have sensitivity to aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs).
Aspirin is usually taken as a handy aid for relieving aches and pains and also as a way to help prevent heart attacks. But, in some cases, its use can be the primary cause of certain diseases.
One such disease, aspirin-exacerbated respiratory disease (AERD), is a common respiratory condition that occurs in people with asthma who have sensitivity to aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs). AERD affects 5 to 10 percent of adults with asthma, around 30 percent of people with severe asthma, and approximately 40 percent of people with asthma plus nasal polyps. New research at Brigham and Women’s Hospital, however, has provided insight into how the disease reveals itself and has helped suggest new treatment options.
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Posted by Brigham and Women's Hospital December 4, 2013
Have you ever wondered why most heart attacks occur in the morning?
Have you ever wondered why most heart attacks occur in the morning? According to recent research from Brigham and Women’s Hospital (BWH) and Oregon Health & Science University, it turns out that your body clock may play a contributing role.
“Our findings suggest that the circadian system, the internal body clock, may contribute to the increased risk for cardiovascular events in the morning,” says study author Frank A.J.L. Scheer, PhD, MSc, Director of the Medical Chronobiology Program at BWH.
Your circadian system regulates and coordinates many of your body’s functions, including metabolism. It tells your body when you should sleep and when you should eat. In this particular study, the researchers found that the body clock drives day/night variations in the quantity of a protein known to be a risk factor for heart attacks and ischemic strokes. The protein is called plasminogen activator inhibitor-1 (PAI-1). It inhibits the breakdown of blood clots and, thus, is a major risk factor for blood clotting.
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Posted by Brigham and Women's Hospital November 5, 2013
Here in the US, antibiotics continue to be frequently prescribed as a treatment for (non-strep) sore throat– a dangerous public health trend.
It has long been understood that antibiotics are an effective and appropriate treatment for strep throat, a bacterial infection, but not for most cases of sore throat. Yet, here in the US, antibiotics continue to be frequently prescribed as a treatment for viral sore throats – a dangerous public health trend.
“We know that antibiotic prescribing, particularly to patients who are not likely to benefit from it, increases the prevalence of antibiotic-resistant bacteria, a growing concern both here in the United States and around the world,” says Jeffrey A. Linder, MD, MPH, a physician and researcher in the Division of General Medicine and Primary Care at Brigham and Women’s Hospital (BWH), and senior author of a recent paper examining antibiotic prescribing rates. “Our research shows that while only 10 percent of adults with sore throat have strep, the only common cause of sore throat requiring antibiotics, the national antibiotic prescribing rate for adults with sore throat has remained at 60 percent.”
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Posted by Brigham and Women's Hospital October 29, 2013
Leah Miriam Urovitch was born on March 30, 2013, healthy and one day ahead of schedule.
Leah Miriam Urovitch was born on March 30, 2013, healthy and one day ahead of schedule. But her parents, Josh, 45, and Lisa, 43, had been waiting for this little girl for years.
Josh and Lisa were married in 2009, and, because of their ages, they started trying to have a baby right away. They continued trying to conceive naturally for more than a year before deciding to seek professional help.
In 2011, they reached out to Dr. Elena Yanushpolsky, an infertility specialist with the Center for Infertility and Reproductive Services (CIRS) at Brigham and Women’s Hospital (BWH). At that point, the primary options for Josh and Lisa were intrauterine insemination (IUI) treatments or in vitro fertilization (IVF).
For IUI, the male partner’s sperm is collected and then injected into the female partner, usually on two consecutive days at the time of ovulation. IVF, on the other hand, is a more involved process and can be broken down into four steps: using medications to stimulate the ovaries to produce multiple mature eggs; surgically removing the eggs; fertilizing and incubating the eggs; and returning the eggs to the uterus by means of a catheter.
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Posted by Brigham and Women's Hospital October 24, 2013
The new robotic surgery simulator is an important tool for physicians new to robotic surgery and experienced robotic surgeons.
The console is identical to the units used in BWH operating rooms, but instead of operating on human patients, surgeons operate in a virtual environment. It’s available to surgeons 24 hours a day, every day, in BWH’s STRATUS Center for Medical Simulation, a facility dedicated to helping health care professionals build their skill sets in simulated environments.
Working with 3-D images that mimic human tissue, surgeons sitting at the simulation console are able to get an accurate visual representation of their proficiency with using the robotic arms and tools. The simulator also records and analyzes a surgeon’s performance throughout a virtual procedure, providing both real-time feedback and a performance report to examine after the procedure.
“Safe robotic surgeons must become one with their operative console, so that the patient-side robot truly functions as an extension of their own body,” says Antonio Gargiulo, MD, Medical Director of the Center for Robotic Surgery at BWH. ”This state-of-the-art simulator should give our patients confidence that their surgeon is always a technically competent robotic surgeon.”
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Posted by Brigham and Women's Hospital October 22, 2013
Dr. Sayeed Malek (pictured) and Dr. Stefan Tullius performed the first pancreas transplant at Brigham and Women's Hospital.
In terms of physical distance, John McDermott, 62, didn’t have to venture very far to become the first pancreas transplant recipient at Brigham and Women’s Hospital (BWH).
John was sitting at his desk at Boston Children’s Hospital, where he has worked as a pharmacist for more than 40 years, when he received the call in the spring of 2007 to come to BWH for a new pancreas. He could have hung up the phone and immediately walked to the BWH operating room across the street, but that would have led to many anxious hours waiting for his new pancreas and the surgical team to be ready. Instead, he drove a few miles to his home in the Savin Hill neighborhood of Dorchester to wait with his wife Chris and have a bite to eat before heading back to BWH.
He had a right to be anxious. He had been living with type 1 diabetes since he was 14 years old, and now he had the opportunity to eliminate a condition that not only reduced his quality of life, but was, in his case, also life threatening.
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Posted by Brigham and Women's Hospital September 18, 2013
BWH obstetrician Audra Robertson, MD, MPH
Brigham and Women’s Hospital (BWH) obstetrician Audra Robertson, MD, MPH, thinks that birth outcomes in our community could be much better. That’s why she spends much of her time advising women on optimizing their health before, during, and after pregnancy, to prevent low birth weight and other problems.
Here are some tips from Dr. Robertson to help women improve their chances of having a healthy baby.
Eating right is particularly important for pregnant women. Your baby needs healthy food, not sugar and fat. Eat plenty of colorful fruits and vegetables, whole grains, calcium-rich foods, and foods low in saturated fat.
Get your vitamins
Get plenty of folic acid and calcium. You can get these and other necessary vitamins and minerals from food and a standard multivitamin. Spinach, oranges, broccoli, and kidney beans are rich in folic acid. Milk, yogurt, and spinach are packed with calcium. A daily prenatal multivitamin, however, can help ensure you get the right amount. Ask your doctor about taking a daily prenatal vitamin.
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Posted by Brigham and Women's Hospital August 15, 2013
Does genetics play a role in the varying rates of cognitive decline among Alzheimer's patients?
Thanks to some intercontinental teamwork, researchers have identified a gene that may help explain why certain Alzheimer’s disease patients experience a more rapid decline in cognitive (thinking) abilities.
Brigham and Women’s Hospital (BWH) medical geneticist Dr. Robert C. Green first recognized that there may be a genetic explanation for why cognitive decline rates vary widely among Alzheimer’s disease patients after analyzing data from a large treatment trial. Even after screening out individuals with vascular disease and other medical conditions known to influence cognition, Dr. Green found that there was still significant variability in the rate of decline among remaining participants.
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Posted by Brigham and Women's Hospital August 13, 2013
The Thornton & Naumes House is a refuge for patients being treated for mesothelioma or other severe lung and throat conditions.
Let’s face it. Going to the hospital, especially for lengthy stays, isn’t pleasant for patients or their families.
Not only are they often dealing with serious injury or illness, but they also are feeling the stress and sadness that comes with being away from home. The Thornton & Naumes House (Mesothelioma House), however, helps resolve some of that unpleasantness by providing a temporary home away from home.
Since 2008, nearly one thousand patients and family members from more than 35 states and eight countries have stayed at the Thornton & Naumes House. Nestled among a row of quaint houses located just steps away from Brigham and Women’s Hospital (BWH), the home is a convenient, comfortable, and affordable refuge for patients being treated for mesothelioma or other severe lung and throat conditions.
An average visit is approximately 19 days, but one family stayed for more than 10 months. Fortunately, thanks to subsidies from generous donors, the fees for these long-term stays are very affordable.
I once visited the house at 48 Francis Street in 2011 to meet a brave teenager from New Jersey, Brianna Ranzino, and her mother, Lisa Ranzino. Brianna had been through a lot. After undergoing a series of surgeries at hospitals throughout the eastern US, Brianna came to BWH in 2010 for an innovative procedure to remove a large tumor from within her chest wall and repair her trachea and esophagus.
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